近三年代表论文和著作：

1.     Nanyu Han^#, Minyuan Tang^#, Sidi   Wan, Zhanbao Jiang, Yong Yue, Xiangui Zhao, Jinrun Yang, Zunxi Huang*, Surface   charge engineering of Thermomyces lanuginosus lipase improves enzymatic   activity and biodiesel synthesis. Biotechnology Letters (2021) 43:   1403-1411.

2.     Huabiao Miao, Yu Ma,   Yuanyuan Zhe, Xianghua Tang, Qian Wu, Zunxi Huang*, Nanyu Han*, Improving   the thermostability of a fungal GH11 xylanase via fusion of a submodule (C2)   from hyperthermophilic CBM9_1-2. International Journal of Molecular   Sciences (2021) 23:463.

3.     Nanyu Han, Justin Tze Yang Ng, Yanpeng Li, Yuguang   Mu*, Zunxi Huang*, Plasticity of the 340-Loop in Influenza Neuraminidase   Offers New Insight for Antiviral Drug Development. International   Journal of Molecular Sciences (2020) 21:5655.

4.     Zhanbao Jiang, Chengbo   Zhang, Minyuan Tang, Bo Xu, Lili Wang, Wen Qian, Jiandong He, Zhihong Zhao,   Qian Wu, Yuelin Mu, Junmei Ding, Rui Zhang, Zunxi Huang*, Nanyu Han*, Improving   the thermostability of Rhizopus Chinensis Lipase through site-directed   mutagenesis based on B-factor analysis. Frontiers in Microbiology   (2020) 11:346.

5.     Nanyu Han^#, Yu Ma^#, Yuelin Mu, Xianghua   Tang, Junjun Li, Zunxi Huang*, Enhancing thermal tolerance of a fungal   GH11 xylanase guided by B-factor analysis and multiple sequence alignment.   Enzyme and Microbial Technology (2019) 131:109422.

6.     Nanyu Han^#, Huabiao Miao^#, Tingting Yu, Bo   Xu, Yunjuan Yang, Qian Wu, Rui Zhang, Zunxi Huang*, Enhancing thermal   tolerance of Aspergillus niger PhyA phytase directed by structural comparison   and computational simulation. BMC Biotechnology (2018) 18:36.

7.     Nanyu Han^#, Huabiao Miao^#, Junmei Ding,   Junjun Li, Yuelin Mu, Junpei Zhou, Zunxi Huang*, Improving the   thermostability of a fungal GH11 xylanase via site-directed mutagenesis   guided by sequence and structural analysis. Biotechnology for Biofuels   (2017) 10:133.

8.     Nanyu Han, Yuguang Mu, Huabiao Miao, Yunjuan Yang,   Qian Wu, Junjun Li, Junmei Ding, Bo Xu, Zunxi Huang*, The 340-cavity in   neuraminidase provides new opportunities for influenza drug   development: A molecular dynamics simulation study. Biochemical   and Biophysical Research Communications (2016), 470(1):130-136.

9.     Nanyu Han, Yuguang Mu*, Locking the 150-cavity   open: In silico design and verification of influenza neuraminidase   inhibitors. PLoS ONE (2013)8:8.

10.     Nanyu Han, Yuguang Mu*, Plasticity of 150-Loop in   influenza neuraminidase explored by Hamiltonian replica exchange molecular   dynamics simulations. PLoS ONE (2013)8:4.

11.     Nanyu Han, Xuewei Liu, Yuguang Mu*, Exploring the   mechanism of Zanamivir resistance in a neuraminidase mutant: A molecular   dynamics study. PLoS ONE (2012)7:9.

12.     Jiahai Shi^#,   Nanyu Han^#, Liangzhong Lim, Shixiong Lua, J. Sivaraman,   Lushan Wang, Yuguang Mu*, Jianxing Song*, Dynamically-driven inactivation   of the catalytic machinery of the SARS 3C-Like protease by the N214A mutation   on the extra domain. PLoS Computational Biology (2011)7:2.

近三年主持的国家级或百万以上其他项目：

1.     国家自然科学基金（32160217）：基于Ser/Thr替换的木聚糖酶XynCDBFV耐热机制及优化策略研究，经费：34万，2022.01-2025.12（主持）

2.     国家自然科学基金（31660240）：流感病毒神经氨酸酶NA与Ca2+的互作机制及药物靶点研究，经费：38万，2017.01-2020.12.（主持）

3.     云南省自然科学面上项目（202201AT070033）：计算机辅助设计提高脂肪酶TLL耐热性及耐热机制研究，10万，2022.06-2025.05（主持）

4.     云南省自然科学青年项目（2016FD018）：高通量筛选抗流感病毒中药组分及作用机制研究，6万，2016.10-2019.09（主持）

5.     云南师范大学优秀青年学者项目，第五批，2021.01-2023.12（主持）

近三年主讲课程：

1.     《现代微生物学及研究方法》

2.     《微生物学实验》

3.     《解密传染病》