近三年代表论文和著作：

* ：通讯作者

（1）             Juan Ni, Ling Zhang,   Tao Zhou, Wei-Jiang Xu, Jing-Lun Xue, Neng Cao, Xu Wang*. Association   between the MTHFR C677T polymorphism, blood folate and vitamin B12 deciency,   and elevated serum total homocysteine in healthy individuals in Yunnan   Province, China. Journal of the Chinese Medical Association, 2017,80,147-153.

（2）             Chao Li, Juan Ni,   Yao-Xian Liu, Han Wang, Zi-Qing Liang, Xu Wang*. Response of MiRNA-22-3p and MiRNA-149-5p to Folate   Deficiency and the Differential Regulation of MTHFR Expression in Normal and   Cancerous Human Hepatocytes. 2017, PLoS One, 12(1):e0168049

（3）             Xihan Guo, Juan Ni,   Jinglun Xue, Xu Wang *. Extract of bulbus Fritillaria cirrhosa perturbs   spindle assembly checkpoint, induces mitotic aberrations and genomic   instability in human colon epithelial cell line. Experimental and Toxicologic   Pathology, 2017,69,163-171

（4）             Xihan Guo, Juan Ni,   Jinglun Xue, Xu Wang *.Phyllanthus emblica Linn. fruit extract potentiates   the anticancer efficacy of mitomycin C and cisplatin and reduces their   genotoxicity to normal cells in vitro. Journal of Zhejiang University-SCIENCE   B (Biomedicine & Biotechnology), 2017, 18(12): 1031- 1045.

（5）             Xihan Guo, Juan Ni,   Xueqin Dai, Tao Zhou, Guofang Yang, Jinglun Xue, Xu Wang*. Biphasic   regulation of spindle assembly checkpoint by low and high concentrations of   resveratrol leads to the opposite effect on chromosomal instability. Mutat   Res Gen Tox En , 2018, 825,19-30.

（6）             Juan Ni; YaoXian Liu;   Tao Zhou; XiaYu Wu; Xu Wang*. Single Nucleotide Polymorphisms in Key   One-Carbon Metabolism Genes and Their Association with Blood Folate and Homocysteine   Levels in a Chinese Population in Yunnan. Genet Test Mol Biomarkers, 2018,   22(3):193-198.

（7）             Juan Ni, Xihan Guo,   Han Wang, Tao Zhou and Xu Wang*. Differences in the Effects of EGCG on   Chromosomal Stability and Cell Growth between Normal and Colon Cancer Cells，Molecules, 2018, 23 (4): pii: E788.

（8）             Han Wang, Juan Ni,   Xihan Guo, Tao Zhou, Xiaoling Ma, Jinglun Xue, Xu Wang*. Shelterin   differentially respond to oxidative stress induced by TiO2-NPs and regulate   telomere length in human hepatocytes and hepatocarcinoma cells in vitro.   BBRC,2018,503,697-702

（9）             Xihan Guo, Han Wang,   Juan Ni, Ziqing Liang, Xiayu Wu, Jinglun Xue and Xu Wang*. Geraniin   selectively promotes cytostasis and apoptosis in human colorectal cancer   cells by inducing catastrophic chromosomal instability. Mutagenesis, 2018,   33, 271-281.

（10）          Xihan Guo, Juan Ni,   Ziqing Liang, Jinglun Xue, Michael Fenech*, Xu Wang*

（11）          The molecular origins   and pathophysiological consequences of micronuclei: New insights into an   age-old problem. Mutation Research-Reviews in Mutation Research, 2019,779 ,   1-35

（12）          朱玉倩，郭锡汉，吴暇玉，徐伟江，汪旭* . 循环microRNA-21在实体肿瘤早期诊断中应用价值的研究进展. 癌变.畸变.突变, 2017,29(2):158-160.

（13）          王晗，倪娟，周滔，杨国防，汪旭*. 纳米颗粒诱导肝脏毒性的研究进展.   癌变.畸变.突变, 2018, 30(4):315-317.

（14）          胡夏练，郭锡汉，马晓玲，汪旭*. 同型半胱氨酸增加阿尔兹海默症患病风险相关机制的研究进展. 癌变.畸变.突变, 2018,30(5):403-406.

（15）          王晗，倪娟，薛京伦，汪旭*. 端粒蛋白复合物shelterin   的结构及功能研究进展. 癌变.畸变.突变, 2019, 31 (3):253-255

（16）          曹宇，倪娟，曹能，杨国防，薛京伦，汪旭*. Gadd45蛋白家族在肿瘤发生发展中的作用. 肿瘤防治研究,   2019,46(3):271-274

（17）          薛京伦，潘雨堃，陈金中，汪旭主编《医学分子遗传学》（第五版），科学出版社，2018.

近三年主持的国家级或百万以上其他项目：

1．国家自然科学基金. MicroRNA应答一碳单位代谢主要组分缺乏并调控错配修复通路核心基

因表达的机制研究 2016,01-2019,12

2. 国家自然科学基金   miRNAs应答同型半胱氨酸代谢变化对人神经细胞Aβ/tau生成与加工路径核心基因表达调控的机制研究 2019,01-2022,12

3. 基因组损伤诊断/矫正数据库建设与干预产品研发, 与华夏基因健康管理集团合作,140万，2015,10-2021,10

近三年主持的省级以上教学质量工程项目：

生物科学-国家级特色专业

分子生物学-国家级双语示范课程

近三年主讲课程（研究生，本科）：

博士生课程：表观遗传学

硕士生课程：遗传毒理学，医学分子遗传学

本科生课程：分子生物学，医学分子遗传学，生命科学进展